Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 1.00 |
| ▸ | PRKACA | P17612 | 4/20 | 1.00 |
| ▸ | PRKACG | P22612 | 4/20 | 1.00 |
| ▸ | PRKACB | P22694 | 4/20 | 1.00 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | GALNT2 | Q10471 | 1/20 | 0.40 |
| ▸ | GALNT1 | Q10472 | 1/20 | 0.40 |
| ▸ | GALNT3 | Q14435 | 1/20 | 0.40 |
| ▸ | GALNT10 | Q86SR1 | 1/20 | 0.40 |
| ▸ | GALNT13 | Q8IUC8 | 1/20 | 0.40 |
| ▸ | GALNT6 | Q8NCL4 | 1/20 | 0.40 |
| ▸ | GALNT14 | Q96FL9 | 1/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987496 | 0.75 | SRC (1.00) | SRCPRKACAPRKACGPRKACBDAO | |
| SCHEMBL7980308 | 0.74 | SRC (1.00) | SRCPRKACAPRKACGPRKACBPKLR | |
| SCHEMBL7984052 | 0.73 | SRC (0.71) | SRCPRKACAPRKACGPRKACBGLI1 | |
| SCHEMBL1205187 | 0.72 | SRC (0.56) | SRCPRKACAPRKACGPRKACBPKLR | |
| SCHEMBL29919698 | 0.71 | SRC (0.53) | SRCPRKACAPRKACGPRKACBPKLR | |
| SCHEMBL20540115 | 0.71 | SRC (0.53) | SRCPRKACAPRKACGPRKACBPKLR | |
| SCHEMBL3883791 | 0.70 | SRC (1.00) | SRCPRKACAPRKACGPRKACBGLI1 | |
| Water SCHEMBL28410001 | 0.69 | SRC (0.52) | SRCPRKACAPRKACGPRKACBPKLR | |
| SCHEMBL9781435 | 0.68 | ESR2 (0.56) | SRCPRKACAPRKACGPRKACBPKLR | |
| SCHEMBL2547457 | 0.68 | SRC (0.58) | SRCPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |