Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 1.00 |
| ▸ | PRKACA | P17612 | 4/20 | 1.00 |
| ▸ | PRKACG | P22612 | 4/20 | 1.00 |
| ▸ | PRKACB | P22694 | 4/20 | 1.00 |
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | GLI1 | P08151 | 2/20 | 0.40 |
| ▸ | GLI2 | P10070 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 4/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | GALNT2 | Q10471 | 1/20 | 0.37 |
| ▸ | GALNT1 | Q10472 | 1/20 | 0.37 |
| ▸ | GALNT3 | Q14435 | 1/20 | 0.37 |
| ▸ | GALNT10 | Q86SR1 | 1/20 | 0.37 |
| ▸ | GALNT13 | Q8IUC8 | 1/20 | 0.37 |
| ▸ | GALNT6 | Q8NCL4 | 1/20 | 0.37 |
| ▸ | GALNT14 | Q96FL9 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880918 | 0.80 | SRC (0.65) | SRCPRKACAPRKACGPRKACBAR | |
| SCHEMBL30143007 | 0.76 | SRC (0.61) | SRCPRKACAPRKACGPRKACBAPP | |
| SCHEMBL1887694 | 0.76 | SRC (0.61) | SRCPRKACAPRKACGPRKACBAPP | |
| SCHEMBL3883791 | 0.75 | SRC (1.00) | SRCPRKACAPRKACGPRKACBAR | |
| SCHEMBL7984263 | 0.74 | SRC (1.00) | SRCPRKACAPRKACGPRKACBGLI1 | |
| SCHEMBL30627692 | 0.71 | SRC (0.55) | SRCPRKACAPRKACGPRKACBAR | |
| SCHEMBL12068041 | 0.69 | CCNB2 (0.60) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL2324326 | 0.69 | AR (1.00) | SRCPRKACAPRKACGPRKACBAR | |
| Acetone SCHEMBL8600747 | 0.69 | APP (0.55) | SRCPRKACAPRKACGPRKACBAPP | |
| SCHEMBL7981735 | 0.68 | SRC (1.00) | SRCPRKACAPRKACGPRKACBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |