Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575511 | 0.94 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1MAPK1MEN1KMT2A | |
| SCHEMBL7086706 | 0.92 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1MAPK1MEN1KMT2A | |
| SCHEMBL2284723 | 0.84 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1MAPK1MEN1KMT2A | |
| SCHEMBL5360505 | 0.84 | CYSLTR2 (0.35) | CYSLTR2CYSLTR1MAPK1MEN1KMT2A | |
| SCHEMBL9761348 | 0.81 | ALOX12 (0.42) | CYSLTR2CYSLTR1MAPK1MEN1KMT2A | |
| SCHEMBL10781131 | 0.80 | USP2 (0.36) | CYSLTR2CYSLTR1MAPK1MEN1KMT2A | |
| SCHEMBL9761889 | 0.79 | ALOX12 (0.45) | CYSLTR2CYSLTR1MAPK1MEN1KMT2A | |
| SCHEMBL5897174 | 0.75 | USP2 (0.35) | MAPK1MEN1KMT2AHTTMAPT | |
| SCHEMBL28702571 | 0.72 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL21884021 | 0.72 | FGF23 (0.39) | MAPK1MEN1KMT2AHTTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277300-B1 | AN EXTRACTANT FOR EXTRACTING METALS FROM AQUEOUS SOLUTIONS OF METAL SALTS COMPRISING AT LEAST ONE O-HYDROXYARYLOXIME CONTAINING AT LEAST 5 ALIPHATIC CARBON ATOMS AND ATLEAST ONE HIGHLY BRANCHED ESTER CONTAINING 10 TO 30 CARBON ATOMS | ZENECA LIMITED (GB) | 2001-08-21 | — | — | US | disclosed |
| US-6113804-A | MIXTURES OF O-HYDROXYARYLOXIMES IN ACIDIC ALIPHATIC HYDROCARBON SOLUTION AND ALIPHATIC OR ALIPHATIC-AROMATIC ESTERS, FOR CHELATION OF COPPER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2000-09-05 | — | — | US | disclosed |
| US-5281336-A | Contacting solution with organic solvent containing o-hydroxyaryloxime extractant and alcohol or ester, separating aqueous phase, contacting organic phase with mineral acid, separating metal in form of salt | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-25 | — | — | US | disclosed |
| US-5176843-A | O-hydroxyaryloximes, alcohol or ester, o-hydroxyarylketoximes; extracting copper | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-05 | — | — | US | disclosed |
| US-4978788-A | COPPER AS PERCHLORATE USING O-HYDROXYARYLOXIMES AND BRANCHED ALIPHATIC OR AROMATIC ALCOHOLS OR ESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-18 | — | — | US | disclosed |
| EP-0202833-A2 | Composition and use of the composition for the extraction of metals from aqueous solutions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-26 | — | — | EP | disclosed |