Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981226 | 0.83 | CYP11B1 (0.58) | CYP11B1CYP11B2 | |
| SCHEMBL3882851 | 0.82 | CYP11B2 (0.56) | CYP11B1CYP11B2 | |
| SCHEMBL7981213 | 0.81 | CYP11B1 (0.73) | CYP11B1CYP11B2 | |
| SCHEMBL19350019 | 0.80 | CYP11B1 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL8129319 | 0.79 | CYP11B2 (0.62) | CYP11B1CYP11B2 | |
| SCHEMBL7995117 | 0.78 | CYP11B1 (0.52) | CYP11B1CYP11B2HDAC1 | |
| SCHEMBL7995116 | 0.78 | CYP11B1 (0.52) | CYP11B1CYP11B2HDAC1 | |
| SCHEMBL8138876 | 0.77 | CYP11B2 (0.56) | CYP11B1CYP11B2 | |
| SCHEMBL3978013 | 0.77 | CYP11B1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL7696780 | 0.77 | CYP11B1 (0.67) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009124-A1 | 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |
| WO-2001009112-A1 | NOVEL 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |