Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995117 | 1.00 | CYP11B1 (0.52) | CYP11B1CYP11B2CA12CA1CA2 | |
| SCHEMBL8325630 | 0.85 | CYP11B1 (0.48) | CYP11B1CYP11B2CA12CA1CA2 | |
| SCHEMBL7990776 | 0.84 | CYP11B1 (0.55) | CYP11B1CYP11B2KDM4ECYP1A2KMT2A | |
| SCHEMBL7990780 | 0.84 | CYP11B1 (0.55) | CYP11B1CYP11B2KDM4ECYP1A2KMT2A | |
| SCHEMBL21334813 | 0.82 | CYP11B1 (0.56) | CYP11B1CYP11B2HDAC3HDAC4HDAC1 | |
| SCHEMBL9641646 | 0.81 | CYP11B1 (0.54) | CYP11B1CYP11B2KDM4EKMT2AMEN1 | |
| SCHEMBL3882851 | 0.80 | CYP11B2 (0.56) | CYP11B1CYP11B2 | |
| SCHEMBL7984428 | 0.78 | CYP11B1 (0.61) | CYP11B1CYP11B2HDAC1 | |
| SCHEMBL8129319 | 0.77 | CYP11B2 (0.62) | CYP11B1CYP11B2KDM4EMAPTKMT2A | |
| SCHEMBL8138876 | 0.75 | CYP11B2 (0.56) | CYP11B1CYP11B2KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009112-A1 | NOVEL 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |