Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984742 | 0.91 | ABCC8 (0.48) | ABCC8KCNJ11HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7991691 | 0.88 | ABCC8 (0.47) | ABCC8KCNJ11HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7985636 | 0.88 | ABCC8 (0.47) | ABCC8KCNJ11HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7987432 | 0.87 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7985468 | 0.87 | ABCC8 (0.47) | ABCC8KCNJ11HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7984524 | 0.86 | HPGD (0.52) | HPGDALDH1A1SMN1; SMN2KMT2ABRD4 | |
| SCHEMBL7988126 | 0.86 | HPGD (0.49) | HPGDALDH1A1SMN1; SMN2KMT2ABRD4 | |
| SCHEMBL7975251 | 0.85 | SMN1; SMN2 (0.60) | HPGDALDH1A1SMN1; SMN2KMT2ABRD4 | |
| SCHEMBL7973932 | 0.84 | SMN1; SMN2 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2ABRD4 | |
| SCHEMBL8059820 | 0.83 | HPGD (0.52) | HPGDALDH1A1SMN1; SMN2KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |