Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985468 | 0.99 | ABCC8 (0.47) | ABCC8KCNJ11HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7984464 | 0.88 | ABCC8 (0.50) | ABCC8KCNJ11HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7988041 | 0.88 | SMN1; SMN2 (0.47) | HPGDALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL7985510 | 0.87 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7988136 | 0.87 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL7984363 | 0.86 | SMN1; SMN2 (0.59) | HPGDALDH1A1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7988727 | 0.86 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7984742 | 0.86 | ABCC8 (0.48) | ABCC8KCNJ11HPGDALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7992062 | 0.85 | SMN1; SMN2 (0.58) | HPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7985636 | 0.85 | ABCC8 (0.47) | ABCC8KCNJ11HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |