Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 5/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972873 | 0.99 | SLC6A2 (0.38) | SLC6A3SLC6A2SLC6A4BACE1MMP2 | |
| SCHEMBL7986018 | 0.79 | ALDH1A1 (0.37) | MMP2MMP3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7972757 | 0.79 | ALDH1A1 (0.36) | MMP2MMP3ALDH1A1 | |
| SCHEMBL8500014 | 0.78 | SMYD3 (0.35) | — | |
| Hydrochloric Acid SCHEMBL8501699 | 0.77 | SMYD3 (0.35) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7986017 | 0.74 | IKBKB (0.45) | — | |
| Hydrochloric Acid SCHEMBL8502684 | 0.74 | SLC6A2 (0.33) | SLC6A2SLC6A4ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8503028 | 0.73 | NMT1 (0.34) | LMNATSHR | |
| SCHEMBL7986012 | 0.73 | ALDH1A1 (0.39) | ALDH1A1LMNATSHR | |
| SCHEMBL8502716 | 0.73 | NTRK1 (0.34) | SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |