Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972751 | 0.99 | ALDH1A1 (0.38) | ALDH1A1BLMDRD4USP2CHRM3 | |
| SCHEMBL7971899 | 0.84 | DRD4 (0.52) | ALDH1A1BLMDRD4USP2CHRM3 | |
| Hydrochloric Acid SCHEMBL7971892 | 0.84 | DRD4 (0.52) | ALDH1A1BLMDRD4USP2CHRM3 | |
| SCHEMBL7982426 | 0.83 | LTA4H (0.47) | ALDH1A1BLMDRD4GRIN2BKCNH2 | |
| Hydrochloric Acid SCHEMBL7971795 | 0.82 | LTA4H (0.47) | ALDH1A1BLMDRD4GRIN2BKCNH2 | |
| SCHEMBL7971755 | 0.82 | DRD4 (0.53) | DRD4KDM4EMEN1TSHRKMT2A | |
| SCHEMBL8525416 | 0.82 | DRD4 (0.48) | ALDH1A1BLMDRD4USP2KDM4E | |
| SCHEMBL7989522 | 0.82 | CHRM4 (0.53) | DRD4GRIN2B | |
| Hydrochloric Acid SCHEMBL7983770 | 0.81 | DRD4 (0.52) | DRD4KDM4EFLT3TYRO3MERTK | |
| SCHEMBL7986622 | 0.81 | DRD4 (0.47) | DRD4KDM4EKMT2AFLT3TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |