Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998550 | 0.83 | PPARG (0.45) | PTGS2PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6535018 | 0.83 | PTGS2 (0.53) | PTGS2PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6248972 | 0.83 | PTGS2 (0.53) | PTGS2PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6534982 | 0.83 | PTGS2 (0.53) | PTGS2PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL28036400 | 0.82 | PTGS2 (0.54) | PTGS2PPARGPPARA | |
| SCHEMBL6535120 | 0.82 | PTGS2 (0.59) | PTGS2PPARGPPARA | |
| SCHEMBL6535047 | 0.81 | PTGS2 (0.52) | PTGS2PPARGPPARA | |
| SCHEMBL28836190 | 0.81 | PTGS2 (0.52) | PTGS2PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6534976 | 0.80 | PTGS2 (0.53) | PTGS2PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6535015 | 0.80 | PTGS2 (0.53) | PTGS2PPARGPPARACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284918-B1 | ENZYME INHIBITORS | VANDERBILT UNIVERSITY | 2001-09-04 | — | — | US | claimed |
| US-6284918-B1 | ENZYME INHIBITORS | VANDERBILT UNIVERSITY | 2001-09-04 | — | — | US | disclosed |