Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.65 |
| ▸ | MAOA | P21397 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | APEX1 | P27695 | 2/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | RAF1 | P04049 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31177135 | 1.00 | TTR (0.65) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL31253344 | 1.00 | TTR (0.65) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL9350283 | 0.92 | TTR (0.76) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL2772226 | 0.84 | MAPT (0.86) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL31177134 | 0.79 | MAPT (0.85) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL7983966 | 0.79 | MAPT (0.85) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL13064957 | 0.79 | TTR (0.74) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL30695849 | 0.79 | TTR (1.00) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL1507679 | 0.79 | TTR (1.00) | TTRMAOAMEN1MAPTKMT2A | |
| SCHEMBL1495097 | 0.79 | TTR (1.00) | TTRMAOAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509413-B2 | Method for making a di(aminoaryl)fluorene compound | CYTEC INDUSTRIES INC. (US) | 2025-12-30 | — | — | US | disclosed |
| EP-3898573-B1 | METHOD FOR MAKING A DI(AMINOARYL)FLUORENE COMPOUND | CYTEC IND INC (US) | 2025-05-28 | — | — | EP | disclosed |
| US-20230278948-A1 | METHOD FOR MAKING A DI(AMINOARYL)FLUORENE COMPOUND | CYTEC INDUSTRIES INC | 2023-09-07 | — | — | US | disclosed |
| US-11685707-B2 | Method for making a di(aminoaryl)fluorene compound | CYTEC INDUSTRIES INC | 2023-06-27 | — | — | US | disclosed |
| US-20220064099-A1 | Method for Making a Di(aminoaryl)fluorene compound | CYTEC INDUSTRIES INC | 2022-03-03 | — | — | US | disclosed |
| CN-113302177-A | Method for producing bis (aminoaryl) fluorene compound | 塞特工业公司 | 2021-08-24 | — | — | CN | disclosed |
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278948-A1 | METHOD FOR MAKING A DI(AMINOARYL)FLUORENE COMPOUND | F12, F3, F2 | TTR 1537/4885MAOA 457/4885MEN1 1191/4885 |
| US-20220064099-A1 | Method for Making a Di(aminoaryl)fluorene compound | F12, F3, F2 | TTR 1263/4885MAOA 348/4885MEN1 1225/4885 |
| US-12509413-B2 | Method for making a di(aminoaryl)fluorene compound | DAO, FGB, CYP2F1 | TTR 1915/4885MAOA 571/4885MEN1 3209/4885 |
| US-11685707-B2 | Method for making a di(aminoaryl)fluorene compound | F12, F3, F2 | TTR 1459/4885MAOA 388/4885MEN1 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.