Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | PDE6A | P16499 | 1/20 | 0.31 |
| ▸ | PDE6G | P18545 | 1/20 | 0.31 |
| ▸ | PDE6B | P35913 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981353 | 0.91 | KIT (0.31) | — | |
| SCHEMBL7982387 | 0.85 | MDM2 (0.36) | — | |
| SCHEMBL1417609 | 0.85 | MDM2 (0.34) | HSD11B1 | |
| SCHEMBL7978754 | 0.84 | HSD11B1 (0.35) | HSD11B2HSD11B1 | |
| SCHEMBL12677421 | 0.80 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL7981311 | 0.78 | BRD4 (0.32) | — | |
| SCHEMBL12671358 | 0.78 | SLC22A12 (0.36) | — | |
| SCHEMBL12671357 | 0.78 | SCN10A (0.34) | — | |
| SCHEMBL7985163 | 0.78 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL7993122 | 0.77 | HSD11B1 (0.36) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |