Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 10/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24411018 | 0.91 | LTA4H (0.61) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4698008 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL7138464 | 0.84 | LTA4H (1.00) | LTA4HNPC1RAB9APSMB1PSMB5 | |
| SCHEMBL991354 | 0.82 | ALDH1A1 (0.76) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL26975791 | 0.81 | LTA4H (0.56) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL22887464 | 0.81 | LTA4H (0.56) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7887532 | 0.81 | ALDH1A1 (0.74) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3647200 | 0.81 | EGFR (0.62) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8536242 | 0.80 | SMN1; SMN2 (0.70) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3366608 | 0.78 | LTA4H (0.78) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |