Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | GLS | O94925 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241355 | 0.88 | LTA4H (0.64) | KDM4EALDH1A1ATMLTA4HMCHR1 | |
| SCHEMBL1241370 | 0.82 | BCHE (0.64) | KDM4EALDH1A1ATMLTA4HL3MBTL1 | |
| SCHEMBL3649395 | 0.82 | MRGPRX4 (0.63) | KDM4ETP53TSHRALDH1A1ROCK2 | |
| Hydrochloric Acid SCHEMBL3647200 | 0.82 | EGFR (0.62) | KDM4ETP53TSHRALDH1A1ROCK2 | |
| SCHEMBL4629303 | 0.82 | KDM4E (0.67) | KDM4ETP53TSHRALDH1A1ROCK2 | |
| SCHEMBL4698008 | 0.81 | KDM4E (0.70) | KDM4ETP53TSHRALDH1A1EPHX2 | |
| SCHEMBL1417060 | 0.81 | L3MBTL1 (0.66) | KDM4ETP53TSHRALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL980503 | 0.81 | KDM4E (0.65) | KDM4ETP53TSHRALDH1A1ROCK2 | |
| SCHEMBL13096987 | 0.80 | MCHR1 (0.68) | KDM4ETP53TSHRALDH1A1LTA4H | |
| SCHEMBL3646371 | 0.80 | KDM4E (0.58) | KDM4ETP53TSHRALDH1A1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |