Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240623 | 0.85 | CA2 (0.53) | CA2CA1MAPK1TSHRTRPV1 | |
| SCHEMBL17363982 | 0.85 | CA2 (0.53) | CA2CA1MAPK1TSHRTRPV1 | |
| SCHEMBL333259 | 0.83 | CA2 (0.68) | CA2CA1MAPK1TSHRALDH1A1 | |
| SCHEMBL10891810 | 0.82 | CA2 (0.67) | CA2CA1MAPK1TSHRMAPT | |
| SCHEMBL6116357 | 0.82 | CA2 (0.60) | CA2CA1MAPK1MAPT | |
| SCHEMBL7217878 | 0.80 | CA2 (0.58) | CA2CA1MAPK1MAPT | |
| SCHEMBL9081169 | 0.80 | CA2 (0.58) | CA2CA1MAPK1MAPT | |
| SCHEMBL28192908 | 0.80 | CA2 (0.58) | CA2CA1MAPK1MAPT | |
| SCHEMBL15164840 | 0.79 | CPB2 (0.49) | CA2CA1MAPK1TSHRMAPT | |
| SCHEMBL9846539 | 0.79 | CPB2 (0.49) | CA2CA1MAPK1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937280-B1 | MULTIFUNCTIONAL MICROSTRUCTURES AND PREPARATION THEREOF | EPIGEM LTD (GB) | 2013-05-29 | — | — | EP | disclosed |
| US-6284072-B1 | Multifunctional microstructures and preparation thereof | EPIGEM LIMITED (GB) | 2001-09-04 | — | — | US | disclosed |
| EP-0937280-A1 | MULTIFUNCTIONAL MICROSTRUCTURES AND PREPARATION THEREOF | Epigem Limited (GB) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998021626-A1 | MULTIFUNCTIONAL MICROSTRUCTURES AND PREPARATION THEREOF | EPIGEM LIMITED (GB) | 1998-05-22 | — | — | WO | disclosed |