Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364367 | 0.84 | PRMT1 (0.64) | PRMT1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7971528 | 0.82 | KMT2A (0.66) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL4278043 | 0.81 | WDR5 (0.52) | ALDH1A1SMN1; SMN2MAPTNPC1RBP4 | |
| SCHEMBL2771812 | 0.80 | KDM4E (0.65) | ALDH1A1LMNASMN1; SMN2MAPTNPC1 | |
| SCHEMBL7971257 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1481753 | 0.78 | DDR1 (0.52) | ALDH1A1SMN1; SMN2MAPTNPC1RBP4 | |
| SCHEMBL2771499 | 0.78 | SMN1; SMN2 (0.62) | ALDH1A1KMT2ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL4653292 | 0.78 | MAPT (0.66) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19212421 | 0.77 | SRPK1 (0.49) | NPY2RSRPK1SIGMAR1 | |
| SCHEMBL7388920 | 0.77 | ALDH1A1 (0.65) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323207-B1 | TREATMENT OR REDUCTION OF TISSUE DAMAGE DUE TO ISCHAEMIA WHICH COMPRISES ADMINISTERING TO A HOST SUFFERING FROM ISCHAEMIA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-27 | — | — | US | disclosed |