Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581237 | 0.97 | USP2 (0.40) | CNR1CNR2SIRT5USP2HSD17B10 | |
| SCHEMBL7998601 | 0.93 | TSHR (0.39) | USP2HSD17B10MAPTMEN1CYP1A2 | |
| SCHEMBL6581222 | 0.86 | LMNA (0.36) | CNR1CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL6579279 | 0.82 | LMNA (0.35) | CNR1CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL6577376 | 0.82 | LMNA (0.33) | CNR1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6579046 | 0.82 | LMNA (0.35) | CNR1HSD17B10MAPTCYP1A2CYP3A4 | |
| SCHEMBL6581167 | 0.82 | LMNA (0.35) | CNR1HSD17B10MAPTCYP1A2CYP3A4 | |
| SCHEMBL6581930 | 0.81 | MAPT (0.39) | CNR1CNR2SIRT5MAPTMEN1 | |
| SCHEMBL6582259 | 0.80 | TRPV1 (0.35) | MAOB | |
| SCHEMBL6582265 | 0.80 | TRPV1 (0.35) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |