Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581237 | 0.96 | USP2 (0.40) | TSHRMAPK10HPGDALDH1A1TDP1 | |
| SCHEMBL7985121 | 0.93 | CNR1 (0.36) | HPGDALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL6581222 | 0.87 | LMNA (0.36) | TSHRHPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6577376 | 0.83 | LMNA (0.33) | HPGDALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL6581167 | 0.82 | LMNA (0.35) | TSHRHPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6579046 | 0.82 | LMNA (0.35) | TSHRHPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6579279 | 0.81 | LMNA (0.35) | TSHRHPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6581961 | 0.81 | LMNA (0.44) | TSHRMAPK10HPGDALDH1A1TDP1 | |
| SCHEMBL6582265 | 0.80 | TRPV1 (0.35) | — | |
| SCHEMBL6582259 | 0.80 | TRPV1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |