Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987464 | 0.88 | HPGD (0.41) | HPGDALDH1A1SMN1; SMN2KMT2ATLR7 | |
| SCHEMBL7984374 | 0.83 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7985247 | 0.82 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7984510 | 0.81 | GAA (0.53) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7987957 | 0.80 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7975251 | 0.79 | SMN1; SMN2 (0.60) | HPGDALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7987432 | 0.78 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7987442 | 0.77 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7985527 | 0.77 | HPGD (0.41) | HPGDALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7984524 | 0.77 | HPGD (0.52) | HPGDALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |