Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987470 | 0.88 | ROCK2 (0.41) | KMT2A | |
| SCHEMBL7984380 | 0.83 | CYP11B1 (0.40) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7985241 | 0.82 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1PTGS2KDM4ESMN1; SMN2 | |
| SCHEMBL7984516 | 0.81 | TP53 (0.53) | LMNA | |
| SCHEMBL7987963 | 0.80 | CNOT7 (0.38) | SMN1; SMN2 | |
| SCHEMBL7975254 | 0.79 | CNOT7 (0.55) | SMN1; SMN2KMT2A | |
| SCHEMBL7987439 | 0.78 | CNOT7 (0.43) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7443281 | 0.78 | CNOT7 (0.46) | HSP90AA1HSP90AB1FYNMEN1KMT2A | |
| SCHEMBL7987444 | 0.77 | PARN (0.42) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7985523 | 0.77 | TDP1 (0.39) | KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |