Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992335 | 0.88 | HPGD (0.44) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7975251 | 0.85 | SMN1; SMN2 (0.60) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7987778 | 0.85 | ALDH1A1 (0.51) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7987444 | 0.84 | PARN (0.42) | HPGDALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL7987957 | 0.81 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2KMT2ABRD4 | |
| SCHEMBL7984374 | 0.81 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7974255 | 0.80 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7973932 | 0.79 | SMN1; SMN2 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7985648 | 0.78 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7987443 | 0.78 | GAA (0.37) | HPGDALDH1A1SMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |