Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974584 | 0.91 | GAA (0.56) | GAANR1H2NR1H3ALDH1A1CYP11B1 | |
| SCHEMBL7985225 | 0.90 | GAA (0.48) | GAAL3MBTL1P2RX7HPGDALDH1A1 | |
| SCHEMBL7985705 | 0.88 | CYP11B1 (0.49) | GAAL3MBTL1HPGDSMN1; SMN2CYP11B1 | |
| SCHEMBL7974018 | 0.87 | GAA (0.53) | GAANR1H2NR1H3ALDH1A1MAPT | |
| SCHEMBL7985325 | 0.86 | HPGD (0.42) | GAAHPGDALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL7985850 | 0.86 | GAA (0.49) | GAANR1H2NR1H3TP53RXFP1 | |
| SCHEMBL7988602 | 0.86 | GAA (0.45) | GAAL3MBTL1P2RX7TLR7TSHR | |
| SCHEMBL7988787 | 0.85 | SMN1; SMN2 (0.42) | GAAHPGDALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL7975267 | 0.84 | SMN1; SMN2 (0.46) | GAANR1H3HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7984888 | 0.84 | HPGD (0.41) | GAAHPGDALDH1A1SMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |