Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985850 | 0.95 | GAA (0.49) | GAANR1H2NR1H3CLK4TP53 | |
| SCHEMBL7974018 | 0.94 | GAA (0.53) | GAANR1H2NR1H3CYP1A2CYP3A4 | |
| SCHEMBL7991874 | 0.92 | GAA (0.48) | GAANR1H2NR1H3CYP1A2CYP3A4 | |
| SCHEMBL7991543 | 0.92 | GAA (0.47) | GAANR1H2NR1H3CYP1A2CYP3A4 | |
| SCHEMBL7985348 | 0.91 | GAA (0.53) | GAANR1H2NR1H3CYP1A2ALDH1A1 | |
| SCHEMBL7974194 | 0.91 | ABCG2 (0.48) | GAANR1H2NR1H3TSHRMAPT | |
| SCHEMBL7985378 | 0.91 | TSHR (0.47) | GAANR1H2NR1H3CYP1A2CYP3A4 | |
| SCHEMBL7974406 | 0.91 | GAA (0.46) | GAANR1H2NR1H3ALDH1A1LMNA | |
| SCHEMBL7985577 | 0.90 | ABCG2 (0.46) | GAANR1H2NR1H3CYP1A2CYP3A4 | |
| SCHEMBL7974093 | 0.90 | GAA (0.48) | GAANR1H2NR1H3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |