Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985225 | 0.95 | GAA (0.48) | CYP11B1CYP11B2GAAMETADORA3 | |
| SCHEMBL7974584 | 0.88 | GAA (0.56) | CYP11B1CYP11B2GAAABCG2ADORA1 | |
| SCHEMBL7974018 | 0.88 | GAA (0.53) | GAAABCG2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7975267 | 0.88 | SMN1; SMN2 (0.46) | CYP11B1CYP11B2GAAADORA3ADORA2B | |
| SCHEMBL7985348 | 0.88 | GAA (0.53) | CYP11B1CYP11B2GAAMETL3MBTL1 | |
| SCHEMBL7984717 | 0.87 | SMN1; SMN2 (0.46) | CYP11B1CYP11B2GAAADORA3NPC1 | |
| SCHEMBL7991405 | 0.86 | CYP11B1 (0.45) | CYP11B1CYP11B2ADORA3HPGDADORA1 | |
| SCHEMBL7974478 | 0.85 | LMNA (0.43) | GAANPC1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL7986521 | 0.85 | CYP11B1 (0.47) | CYP11B1CYP11B2METADORA3NPC1 | |
| SCHEMBL7974490 | 0.84 | NR1H4 (0.47) | CYP11B1CYP11B2ADORA3ADORA2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |