Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12537066 | 0.90 | HTR2C (0.46) | HTR2CHTR2AHTR2BHPGDKMT2A | |
| SCHEMBL14069048 | 0.88 | HTR2C (0.46) | HTR2CHTR2AHTR2BCRBNSLC18A3 | |
| SCHEMBL29501341 | 0.87 | SLC18A3 (0.53) | HTR2CHTR2AHTR2BHRH3SLC18A3 | |
| SCHEMBL2657988 | 0.87 | SLC18A3 (0.53) | HTR2CHTR2AHTR2BHRH3SLC18A3 | |
| Bromide SCHEMBL6423364 | 0.86 | SLC18A3 (0.51) | HTR2CHTR2AHTR2BHRH3SLC18A3 | |
| Hydrochloric Acid SCHEMBL5271851 | 0.86 | SLC18A3 (0.51) | HTR2CHTR2AHTR2BHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL29877056 | 0.86 | SLC18A3 (0.51) | HTR2CHTR2AHTR2BHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL16835555 | 0.86 | SLC18A3 (0.51) | HTR2CHTR2AHTR2BHPGDKMT2A | |
| SCHEMBL11265606 | 0.84 | HRH3 (0.53) | KCNH2HRH3CRBNSLC18A3 | |
| SCHEMBL11639039 | 0.82 | HTR2C (0.58) | HTR2CHTR2AHTR2BHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144900-A1 | SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2018-08-09 | — | — | WO | disclosed |
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |