Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7988727 | 0.99 | HPGD (0.46) | HPGDSMN1; SMN2ALDH1A1KMT2ABRDT | |
| SCHEMBL7988041 | 0.90 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2ALDH1A1KMT2ACYP11B2 | |
| Hydrochloric Acid SCHEMBL7988136 | 0.89 | HPGD (0.47) | HPGDSMN1; SMN2ALDH1A1KMT2ACYP11B2 | |
| SCHEMBL7984363 | 0.88 | SMN1; SMN2 (0.59) | HPGDSMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7992062 | 0.87 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7984524 | 0.87 | HPGD (0.52) | HPGDSMN1; SMN2ALDH1A1KMT2ABRDT | |
| SCHEMBL7989507 | 0.87 | HPGD (0.46) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL7991691 | 0.87 | ABCC8 (0.47) | HPGDSMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7985468 | 0.86 | ABCC8 (0.47) | HPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7988953 | 0.85 | HPGD (0.45) | HPGDSMN1; SMN2ALDH1A1KMT2ABRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |