Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984748 | 0.90 | ABCC8 (0.48) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| SCHEMBL7984470 | 0.88 | ABCC8 (0.50) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| SCHEMBL7975139 | 0.88 | CNOT7 (0.40) | CNOT7PARNLMNAMAPK1MEN1 | |
| SCHEMBL7991686 | 0.86 | ABCC8 (0.48) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| SCHEMBL7974307 | 0.85 | CNOT7 (0.40) | CNOT7PARNLMNAMEN1KMT2A | |
| SCHEMBL7985640 | 0.85 | CNOT7 (0.53) | CNOT7PARNKMT2APNPBRD4 | |
| Hydrochloric Acid SCHEMBL7985467 | 0.85 | ABCC8 (0.47) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| Hydrochloric Acid SCHEMBL7987619 | 0.84 | CNOT7 (0.52) | CNOT7PARNKMT2APNPBRD4 | |
| SCHEMBL7985636 | 0.83 | ABCC8 (0.47) | ABCC8KCNJ11NR1H4SCN9ALMNA | |
| SCHEMBL7988524 | 0.82 | ABCC8 (0.47) | ABCC8KCNJ11CNOT7PARNNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |