Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.48 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985467 | 0.99 | ABCC8 (0.47) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| SCHEMBL7984470 | 0.89 | ABCC8 (0.50) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| SCHEMBL7988039 | 0.87 | CNOT7 (0.41) | CNOT7PARNLMNAMAPK1MEN1 | |
| SCHEMBL7984748 | 0.87 | ABCC8 (0.48) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| Hydrochloric Acid SCHEMBL7988145 | 0.86 | CNOT7 (0.40) | CNOT7PARNLMNAMAPK1MEN1 | |
| SCHEMBL7985516 | 0.86 | CNOT7 (0.40) | CNOT7PARNLMNAMEN1KMT2A | |
| SCHEMBL7984366 | 0.86 | CNOT7 (0.53) | CNOT7PARNKMT2AADORA2BSMN1; SMN2 | |
| SCHEMBL7985645 | 0.86 | ABCC8 (0.47) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| Hydrochloric Acid SCHEMBL7988733 | 0.85 | CNOT7 (0.40) | CNOT7PARNLMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7992068 | 0.85 | CNOT7 (0.52) | CNOT7PARNKMT2AADORA2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |