Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975251 | 0.87 | SMN1; SMN2 (0.60) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL7973932 | 0.85 | SMN1; SMN2 (0.53) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL7974255 | 0.84 | HPGD (0.47) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL7111737 | 0.84 | PNP (0.49) | HPGDSMN1; SMN2ALDH1A1KMT2ADAO | |
| SCHEMBL7984510 | 0.84 | GAA (0.53) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL7987432 | 0.83 | HPGD (0.47) | HPGDSMN1; SMN2ALDH1A1KMT2ABRD4 | |
| SCHEMBL7984206 | 0.83 | HPGD (0.46) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL7984753 | 0.83 | SMN1; SMN2 (0.51) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL6258586 | 0.83 | PNP (0.48) | HPGDSMN1; SMN2ALDH1A1KMT2ADAO | |
| SCHEMBL7987778 | 0.83 | ALDH1A1 (0.51) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |