Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975251 | 0.90 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7973932 | 0.86 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7987442 | 0.85 | HPGD (0.46) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7988126 | 0.83 | HPGD (0.49) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7987785 | 0.83 | PARN (0.47) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7985648 | 0.83 | HPGD (0.47) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7992335 | 0.82 | HPGD (0.44) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7985339 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7987432 | 0.82 | HPGD (0.47) | ALDH1A1SMN1; SMN2HPGDKMT2ABRD4 | |
| SCHEMBL7974513 | 0.82 | ADORA3 (0.53) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |