SCHEMBL798583

SCHEMBL798583

C=CCNc1ccc2ccc(=O)oc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 8/20 0.61
CA12 O43570 6/20 0.52
CA1 P00915 6/20 0.52
CA9 Q16790 5/20 0.52
SRD5A1 P18405 2/20 0.51
MAOB P27338 1/20 0.48
DRD2 P14416 5/20 0.46
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
GLA P06280 2/20 0.45
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
AKR1B1 P15121 1/20 0.45
HPGD P15428 1/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
KMT2A Q03164 1/20 0.45
MCL1 Q07820 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1772426 0.89 ACHE (0.54) DRD4CA12CA1CA9SRD5A1
SCHEMBL9474175 0.79 DRD4 (0.67) DRD4CA12CA1CA9MAOB
SCHEMBL3197214 0.78 DRD4 (0.69) DRD4CA12CA1CA9MAOB
SCHEMBL22899134 0.78 DRD4 (0.69) DRD4CA12CA1CA9MAOB
SCHEMBL22501750 0.77 CA12 (0.65) CA12CA1CA9MAOBKDM4E
SCHEMBL5775239 0.75 CA12 (0.50) CA12CA1CA9KDM4EALDH1A1
SCHEMBL7917887 0.74 CA12 (0.52) DRD4CA12CA1CA9SRD5A1
SCHEMBL18087828 0.74 DRD4 (0.59) DRD4CA12CA1CA9MAOB
SCHEMBL16271239 0.73 SRD5A1 (0.60) DRD4CA12CA1CA9SRD5A1
SCHEMBL5567249 0.73 DRD4 (0.58) DRD4CA12CA1CA9MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200032171-A1 Laundry Method, Use of Polypeptide and Detergent Composition NOVOZYMES A/S (DK) 2020-01-30 US claimed
US-20240228913-A1 ENZYME COMPOSITIONS AND USES THEREOF NOVOZYMES A/S (DK) 2024-07-11 US disclosed
EP-3362556-B1 POLYPEPTIDE VARIANTS NOVOZYMES AS (DK) 2024-07-10 EP disclosed
US-12031112-B2 Detergent composition THE PROCTER & GAMBLE COMPANY (US) 2024-07-09 US disclosed
US-20240218299-A1 CLEANING COMPOSITIONS CONTAINING DISPERSINS II HENKEL AG & CO. KGAA (DE) 2024-07-04 US disclosed
US-20240209335-A1 Cleaning Compositions Comprising Enzymes NOVOZYMES A/S (DK) 2024-06-27 US disclosed
WO-2024131880-A2 DETERGENT COMPOSITION COMPRISING CATALASE AND AMYLASE NOVOZYMES A/S (DK) 2024-06-27 WO disclosed
US-20240209340-A1 Polypeptides having Peptidoglycan Degrading Activity and Polynucleotides Encoding Same NOVOZYMES A/S (DK) 2024-06-27 US disclosed
US-12018236-B2 Detergent composition NOVOZYMES A/S (DK) 2024-06-25 US disclosed
WO-2024126483-A1 IMPROVED LIPASE (GCL1) VARIANTS NOVOZYMES A/S (DK) 2024-06-20 WO disclosed
US-4619779-A ALIPHATIC PEROXY CARBOXYLIC ACID BLEACH PRECURSOR ON FLEXIBLE SUBSTRATE THE PROCTER & GAMBLE COMPANY (US) 1986-10-28 US disclosed
EP-0057088-B1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1985-08-21 EP disclosed
US-4536314-A PLEASANT ODOR THE PROCTER & GAMBLE COMPANY (US) 1985-08-20 US disclosed
EP-0120591-A1 Detergent ingredients, and their use in cleaning compositions and washing processes THE PROCTER & GAMBLE COMPANY (US) 1984-10-03 EP disclosed
EP-0118191-A1 Laundry additive compositions THE PROCTER & GAMBLE COMPANY (US) 1984-09-12 EP disclosed
EP-0098129-A1 Detergent additive product THE PROCTER & GAMBLE COMPANY (US) 1984-01-11 EP disclosed
US-4417994-A STORAGE SENSITIVE PORPHINE PHOTACTIVATOR DYE ENCLOSED BY PHOSPHATE MATRIX THE PROCTER & GAMBLE COMPANY (US) 1983-11-29 US disclosed
US-4399049-A PARTICLES EXTRUDED WITH ETHOXYLATED NONIONIC SURFACTANT; STORAGE STABILITY; RABID DISPERSION; LAUNDERING THE PROCTER & GAMBLE COMPANY (US) 1983-08-16 US disclosed
EP-0062523-A2 Detergent additive compositions and preparations and use thereof in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-13 EP disclosed
EP-0057088-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-08-04 EP disclosed