Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 14/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.31 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110666 | 0.80 | ALDH1A1 (0.51) | PDE4BMAPTPLIN1LMNAGAA | |
| SCHEMBL7985943 | 0.76 | PDE4D (0.64) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7110388 | 0.76 | PDE4D (0.64) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7107092 | 0.76 | PDE4D (0.39) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7431497 | 0.70 | CA12 (0.52) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL1388372 | 0.65 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL1388370 | 0.65 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL1074318 | 0.65 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL1076338 | 0.64 | CYP1A1 (0.59) | NR1H2MAPTALDH1A1 | |
| SCHEMBL3931400 | 0.64 | CYP1A1 (0.59) | NR1H2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255326-B1 | ANTIINFLAMMATORY AGENT; AUTOIMMUNE DISEASES | AVENTIS PHARMA LIMITED (GB) | 2001-07-03 | — | — | US | disclosed |