Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | VNN1 | O95497 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972494 | 0.96 | MAOB (0.55) | GAAVNN1SMN1; SMN2HTTNPC1 | |
| SCHEMBL7986109 | 0.96 | MAOB (0.55) | GAAVNN1SMN1; SMN2HTTNPC1 | |
| SCHEMBL7983889 | 0.95 | MAOB (0.54) | GAAVNN1SMN1; SMN2HTTNPC1 | |
| SCHEMBL7983783 | 0.95 | MAOB (0.54) | GAAVNN1SMN1; SMN2HTTNPC1 | |
| SCHEMBL7982716 | 0.95 | MAOB (0.54) | GAAVNN1SMN1; SMN2HTTNPC1 | |
| SCHEMBL7534226 | 0.87 | EPHX2 (0.53) | SMN1; SMN2ALDH1A1DRD2DRD3HRH3 | |
| SCHEMBL7989764 | 0.87 | GAA (0.53) | GAAVNN1SMN1; SMN2HTTNPC1 | |
| SCHEMBL17142140 | 0.86 | HDAC2 (0.64) | GAAVNN1SMN1; SMN2HTTNPC1 | |
| SCHEMBL5091359 | 0.85 | CHRM3 (0.54) | GAAVNN1CHRM3 | |
| SCHEMBL7233161 | 0.85 | CHRM3 (0.54) | GAAVNN1CHRM3SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |