Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | VNN1 | O95497 | 1/20 | 0.60 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CFD | P00746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365904 | 0.91 | MAOA (0.66) | HDAC2HDAC8HDAC6MAOACHRM3 | |
| SCHEMBL28146231 | 0.89 | CHRM3 (0.55) | HDAC2HDAC8HDAC6MAOACHRM3 | |
| SCHEMBL5094235 | 0.88 | ROCK2 (0.59) | HDAC2HDAC8HDAC6MAOACHRM3 | |
| SCHEMBL22304851 | 0.88 | HDAC2 (0.59) | HDAC2HDAC8HDAC6MAOAALDH1A1 | |
| SCHEMBL6237491 | 0.88 | EPHX2 (0.54) | HDAC2HDAC8HDAC6MAOACHRM3 | |
| SCHEMBL5091359 | 0.87 | CHRM3 (0.54) | HDAC2HDAC8HDAC6MAOACHRM3 | |
| SCHEMBL7233161 | 0.87 | CHRM3 (0.54) | HDAC2HDAC8HDAC6MAOACHRM3 | |
| SCHEMBL7985996 | 0.86 | GAA (0.56) | CHRM3VNN1ALDH1A1GAAHTT | |
| SCHEMBL7989764 | 0.86 | GAA (0.53) | HDAC2HDAC8HDAC6MAOACHRM3 | |
| SCHEMBL8360303 | 0.85 | HDAC6 (0.57) | HDAC2HDAC8HDAC6MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137413-A1 | NOVEL HALOGEN-SUBSTITUTED COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | US | disclosed |
| EP-3126353-A1 | NOVEL 3-[(PYRAZOL-5-YL)-HETEROARYL]-BENZAMIDE DERIVATIVES AND USE THEREOF AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-02-08 | — | — | EP | disclosed |
| WO-2015150442-A1 | NOVEL 3-[(PYRAZOL-5-YL)-HETEROARYL]-BENZAMIDE DERIVATIVES AND USE THEREOF AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137413-A1 | NOVEL HALOGEN-SUBSTITUTED COMPOUNDS | CYP4F3, PYM1, PRDX4 | HDAC2 2780/4885HDAC8 4268/4885HDAC6 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.