Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972753 | 0.99 | DRD4 (0.45) | DRD4SIGMAR1KMT2ACXCR3FLT3 | |
| SCHEMBL7971899 | 0.92 | DRD4 (0.52) | DRD4SIGMAR1CXCR3FLT3TYRO3 | |
| Hydrochloric Acid SCHEMBL7971892 | 0.91 | DRD4 (0.52) | DRD4SIGMAR1CXCR3FLT3TYRO3 | |
| SCHEMBL7971755 | 0.89 | DRD4 (0.53) | DRD4SIGMAR1KMT2ACXCR3FLT3 | |
| Hydrochloric Acid SCHEMBL7983770 | 0.89 | DRD4 (0.52) | DRD4SIGMAR1CXCR3FLT3TYRO3 | |
| SCHEMBL8525416 | 0.87 | DRD4 (0.48) | DRD4SIGMAR1KMT2ACXCR3FLT3 | |
| SCHEMBL7986622 | 0.87 | DRD4 (0.47) | DRD4SIGMAR1KMT2ACXCR3FLT3 | |
| SCHEMBL7986721 | 0.87 | DRD4 (0.47) | DRD4SIGMAR1KMT2ACXCR3FLT3 | |
| SCHEMBL7987631 | 0.87 | DRD4 (0.47) | DRD4SIGMAR1KMT2ACXCR3FLT3 | |
| SCHEMBL7982426 | 0.87 | LTA4H (0.47) | DRD4LTA4HALDH1A1BLMCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |