Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982578 | 0.83 | TMPRSS2 (0.64) | F10ITGB3ITGA2BTMPRSS2LMNA | |
| SCHEMBL7419632 | 0.81 | PRSS1 (0.64) | F10ITGB3ITGA2BTMPRSS2LMNA | |
| SCHEMBL7984857 | 0.81 | EPHX2 (0.65) | EPHX2AKR1B1PPARALMNASMN1; SMN2 | |
| SCHEMBL7986829 | 0.80 | PRMT1 (0.65) | F10ITGB3ITGA2BTMPRSS2LMNA | |
| SCHEMBL7989663 | 0.80 | PRMT1 (0.65) | F10ITGB3ITGA2BTMPRSS2LMNA | |
| SCHEMBL7427347 | 0.80 | PRMT1 (0.65) | F10ITGB3ITGA2BTMPRSS2LMNA | |
| SCHEMBL7986010 | 0.80 | PRSS1 (0.63) | F10ITGB3ITGA2BEPHX2TMPRSS2 | |
| SCHEMBL7972474 | 0.79 | TMPRSS2 (0.57) | F10ITGB3ITGA2BTMPRSS2LMNA | |
| SCHEMBL7982523 | 0.79 | EPHX2 (0.65) | EPHX2AKR1B1PPARALMNASMN1; SMN2 | |
| SCHEMBL7972008 | 0.78 | F10 (0.62) | F10ITGB3ITGA2BTMPRSS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |