Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7989779 | 0.99 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAHTTDRD4ALDH1A1 | |
| SCHEMBL7983020 | 0.93 | GSK3B (0.47) | SMN1; SMN2LMNAHTTDRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7989390 | 0.92 | GSK3B (0.46) | SMN1; SMN2LMNAHTTDRD4ALDH1A1 | |
| SCHEMBL7971581 | 0.88 | LMNA (0.42) | SMN1; SMN2LMNADRD4ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7971812 | 0.88 | LMNA (0.42) | SMN1; SMN2LMNADRD4ALDH1A1KDM4E | |
| SCHEMBL7983350 | 0.86 | FAAH (0.38) | SMN1; SMN2LMNADRD4ALDH1A1GSK3B | |
| SCHEMBL7982581 | 0.85 | CCR3 (0.46) | GSK3B | |
| Hydrochloric Acid SCHEMBL7972026 | 0.85 | FAAH (0.37) | SMN1; SMN2LMNADRD4ALDH1A1GSK3B | |
| Hydrochloric Acid SCHEMBL7983273 | 0.85 | CCR3 (0.45) | GSK3B | |
| SCHEMBL7989275 | 0.84 | CCR3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |