Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056959 | 0.88 | NR1H4 (0.39) | HPGDSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL7988683 | 0.87 | GAA (0.38) | MAOBHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7984888 | 0.85 | HPGD (0.41) | HPGDSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL7985325 | 0.85 | HPGD (0.42) | HPGDSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL7988787 | 0.84 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL7975267 | 0.84 | SMN1; SMN2 (0.46) | HPGDSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL7974490 | 0.82 | NR1H4 (0.47) | HPGDSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7985348 | 0.81 | GAA (0.53) | HPGDSMN1; SMN2ALDH1A1GAARXFP1 | |
| SCHEMBL7988558 | 0.80 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL7988594 | 0.80 | TP53 (0.44) | HPGDSMN1; SMN2ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |