Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 11/20 | 0.53 |
| ▸ | TMPRSS6 | Q8IU80 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423694 | 0.92 | RAB9A (0.56) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7389439 | 0.91 | RAB9A (0.55) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7982625 | 0.91 | RAB9A (0.55) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7986806 | 0.90 | RAB9A (0.54) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7986111 | 0.90 | RAB9A (0.54) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7984063 | 0.90 | RAB9A (0.54) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL10035190 | 0.88 | HTT (0.58) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7420940 | 0.87 | F10 (0.56) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7986856 | 0.82 | HTT (0.57) | F10F2TMPRSS6RAB9AHTT | |
| SCHEMBL7538755 | 0.80 | PRSS1 (0.59) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | claimed |