Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989746 | 0.92 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2AMAPK1CYP2C19 | |
| SCHEMBL7989492 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2ATSHRPOLB | |
| SCHEMBL7989148 | 0.78 | CHRM2 (0.39) | — | |
| SCHEMBL7985907 | 0.74 | L3MBTL1 (0.38) | SMN1; SMN2MEN1KMT2AMAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL7989639 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2AMAPK1PTGS2 | |
| SCHEMBL28268129 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AMAPK1PTGS2 | |
| SCHEMBL700361 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AMAPK1PTGS2 | |
| SCHEMBL13513393 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AMAPK1PTGS2 | |
| SCHEMBL700362 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AMAPK1PTGS2 | |
| SCHEMBL700698 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AMAPK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |