Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993429 | 0.92 | CHRM2 (0.36) | L3MBTL1GAAKMT2AATMALDH1A1 | |
| SCHEMBL7989252 | 0.81 | RAB9A (0.35) | GAAKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL7985658 | 0.78 | CHRM2 (0.39) | GAAJAK1CHRM1 | |
| SCHEMBL7986449 | 0.74 | SMN1; SMN2 (0.40) | KMT2AALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8221697 | 0.74 | GPR65 (0.48) | GPR65JAK2JAK1TYK2CHRM1 | |
| SCHEMBL11360559 | 0.74 | CHRM1 (0.36) | KMT2AALDH1A1MEN1GPR65CHRM1 | |
| Hydrochloric Acid SCHEMBL7987411 | 0.74 | HTR2A (0.38) | L3MBTL1GAAKMT2AATMALDH1A1 | |
| SCHEMBL28268013 | 0.73 | KMT2A (0.36) | L3MBTL1GAAKMT2AATMALDH1A1 | |
| SCHEMBL11368483 | 0.72 | GPR65 (0.34) | L3MBTL1GAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4051790 | 0.71 | HPGD (0.40) | L3MBTL1GAAKMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009125-A1 | NOVEL 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |