Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12967485 | 0.81 | KCNH2 (0.58) | MAPTTDP1IDO1CHRM2ADRA2A | |
| SCHEMBL17704778 | 0.80 | CHRM2 (0.77) | MAPTTDP1CHRM2ADRA2AKCNH2 | |
| SCHEMBL12967486 | 0.80 | CHRM2 (0.77) | MAPTTDP1CHRM2ADRA2AKCNH2 | |
| SCHEMBL17817181 | 0.76 | POLB (0.64) | MAPTPOLBKMT2ATDP1GAA | |
| SCHEMBL8006419 | 0.76 | POLB (0.64) | MAPTPOLBKMT2ATDP1GAA | |
| SCHEMBL2551575 | 0.76 | HSP90AA1 (0.65) | MAPTPOLBKMT2ATDP1GAA | |
| SCHEMBL16702858 | 0.76 | CHRM2 (0.75) | MAPTTDP1CHRM2ADRA2AKCNH2 | |
| SCHEMBL14113503 | 0.72 | ADRA1D (0.58) | MAPTTDP1CHRM2ADRA2AKCNH2 | |
| SCHEMBL3395176 | 0.72 | IDO1 (0.47) | POLBL3MBTL1IDO1SMN1; SMN2ADRB2 | |
| SCHEMBL14434181 | 0.72 | POLB (0.61) | MAPTPOLBKMT2ATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274596-B1 | MICROBIOCIDES FOR DRUG RESISTANCE INFECTIONS | ANADYS PHARMACEUTICALS, INC. | 2001-08-14 | — | — | US | disclosed |
| WO-2000024389-A2 | BENZOQUINOLINE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | ANADYS PHARMACEUTICALS, INC. (US) | 2000-05-04 | — | — | WO | disclosed |