Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 5/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.55 |
| ▸ | TACR1 | P25103 | 9/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
| ▸ | NMBR | P28336 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975820 | 1.00 | IL1RN (0.55) | IL1RNERAP2ERAP1TACR1LNPEP | |
| SCHEMBL7993348 | 1.00 | IL1RN (0.55) | IL1RNERAP2ERAP1TACR1LNPEP | |
| SCHEMBL7975993 | 0.88 | ERAP1 (0.53) | IL1RNERAP2ERAP1TACR1LNPEP | |
| SCHEMBL7993776 | 0.85 | ERAP2 (0.52) | IL1RNERAP2ERAP1TACR1LNPEP | |
| SCHEMBL7989620 | 0.85 | NMBR (0.55) | IL1RNERAP2ERAP1NMBR | |
| SCHEMBL7989931 | 0.84 | EDNRA (0.42) | IL1RNERAP2ERAP1 | |
| SCHEMBL7976141 | 0.84 | ITGB2 (0.58) | IL1RNERAP2ERAP1NMBR | |
| SCHEMBL7990279 | 0.82 | LMNA (0.58) | IL1RNERAP2ERAP1TACR1LNPEP | |
| SCHEMBL7976137 | 0.82 | ITGB2 (0.59) | NMBR | |
| SCHEMBL7990294 | 0.82 | ITGB2 (0.59) | NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| WO-2001009124-A1 | 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |
| EP-0792265-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |