Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | GAA | P10253 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | IDO1 | P14902 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175227 | 0.87 | MAPT (0.86) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL22024982 | 0.86 | SMN1; SMN2 (0.75) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL12412637 | 0.84 | ALDH1A1 (0.76) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL12404443 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL22567749 | 0.82 | MAPT (0.78) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL22567938 | 0.82 | MAPT (0.78) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL12347771 | 0.81 | MAPT (0.69) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL22065211 | 0.81 | MAPT (0.72) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL2467470 | 0.81 | IDO1 (1.00) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT | |
| SCHEMBL26491182 | 0.81 | LMNA (0.71) | SMN1; SMN2NPSR1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |