Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990089 | 0.89 | EDNRA (0.60) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7987491 | 0.88 | EDNRA (0.61) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7993185 | 0.86 | EDNRA (0.57) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7987077 | 0.84 | NPC1 (0.55) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7986890 | 0.83 | EDNRA (0.52) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7993516 | 0.79 | EDNRA (0.59) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9501146 | 0.76 | NPC1 (0.56) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10940868 | 0.74 | NPC1 (0.58) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19625532 | 0.74 | NPC1 (0.58) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7439246 | 0.74 | NPC1 (0.58) | EDNRANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |