Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | EDNRA | P25101 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429787 | 0.92 | NPC1 (0.58) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL10940868 | 0.92 | NPC1 (0.58) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL19625532 | 0.92 | NPC1 (0.58) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL7439246 | 0.92 | NPC1 (0.58) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL12069024 | 0.82 | TRPM8 (0.58) | ALDH1A1MAPTTSHRATMSMN1; SMN2 | |
| SCHEMBL8150285 | 0.82 | TRPM8 (0.58) | ALDH1A1MAPTTSHRATMSMN1; SMN2 | |
| SCHEMBL9502166 | 0.81 | TAS1R3 (0.50) | EDNRATAS1R3TAS1R1CYP3A4 | |
| SCHEMBL28618890 | 0.80 | TRPM8 (0.54) | ALDH1A1TSHRRAB9AATMSMN1; SMN2 | |
| SCHEMBL7987491 | 0.80 | EDNRA (0.61) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL10363640 | 0.80 | TRPM8 (0.49) | ALDH1A1TRPM8CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375554-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-DIHYDROXYPHENYLSERINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0375554-A2 | Process for producing optically active threo-dihydroxyphenylserine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | disclosed |