Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.74 |
| ▸ | FLT1 | P17948 | 4/20 | 0.74 |
| ▸ | FLT4 | P35916 | 4/20 | 0.74 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986816 | 0.88 | KDR (0.58) | KDRFLT1FLT4PRKACAPRKACG | |
| SCHEMBL7554934 | 0.87 | KDR (0.55) | KDRFLT1FLT4PRKACAPRKACG | |
| SCHEMBL7504511 | 0.86 | KDR (0.54) | KDRFLT1FLT4PRKACAPRKACG | |
| SCHEMBL7553622 | 0.85 | KDR (0.55) | KDRFLT1FLT4CYP2A6TDP2 | |
| SCHEMBL7547755 | 0.85 | KDR (1.00) | KDRFLT1FLT4CYP2A6PRKACA | |
| SCHEMBL7551047 | 0.84 | KDR (0.51) | KDRFLT1FLT4PRKACAPRKACG | |
| SCHEMBL7557466 | 0.83 | KDR (0.73) | KDRFLT1FLT4CYP2A6TDP2 | |
| SCHEMBL7552915 | 0.83 | KDR (0.51) | KDRFLT1FLT4PRKACAPRKACG | |
| SCHEMBL7988018 | 0.83 | KDR (0.78) | KDRFLT1FLT4CYP2A6TDP2 | |
| SCHEMBL7976429 | 0.83 | KDR (0.78) | KDRFLT1FLT4CYP2A6TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |