Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987174 | 1.00 | YAP1 (0.53) | YAP1ITGB3ITGA2BITGAVP2RX7 | |
| SCHEMBL7986551 | 0.83 | ITGB3 (0.71) | YAP1ITGB3ITGA2BITGAVP2RX7 | |
| SCHEMBL7292244 | 0.83 | ITGB3 (0.71) | YAP1ITGB3ITGA2BITGAVP2RX7 | |
| SCHEMBL7272131 | 0.81 | YAP1 (0.71) | YAP1ITGB3ITGA2BITGAVP2RX7 | |
| SCHEMBL7988198 | 0.80 | ITGB3 (0.45) | YAP1ITGB3ITGA2BITGAV | |
| SCHEMBL24336797 | 0.79 | YAP1 (0.66) | YAP1ITGB3ITGA2BITGAVP2RX7 | |
| SCHEMBL7282664 | 0.78 | YAP1 (0.72) | YAP1ITGB3ITGA2BITGAVP2RX7 | |
| SCHEMBL3008274 | 0.78 | YAP1 (0.60) | YAP1ITGB3ITGA2BP2RX7MAPK1 | |
| SCHEMBL3008280 | 0.78 | YAP1 (0.60) | YAP1ITGB3ITGA2BP2RX7MAPK1 | |
| SCHEMBL12652625 | 0.78 | YAP1 (0.60) | YAP1ITGB3ITGA2BP2RX7MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248304-B1 | PIPERIDINE COMPOUND | BERLEX LABORATORIES, INC. | 2001-06-19 | — | — | US | disclosed |