Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833499 | 0.83 | LMNA (0.34) | LMNAPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL28160872 | 0.80 | PRSS1 (0.34) | LMNAPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL1712905 | 0.79 | KMT2A (0.41) | LMNAKMT2AF2 | |
| SCHEMBL6292013 | 0.77 | LMNA (0.33) | LMNAPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL7975214 | 0.76 | — | — | |
| SCHEMBL8133375 | 0.75 | PRSS1 (0.36) | PRSS1PRSS2C1SPRSS3RECQL | |
| SCHEMBL1947313 | 0.75 | PRSS1 (0.31) | PRSS1PRSS2C1SPRSS3RECQL | |
| SCHEMBL750508 | 0.72 | ALDH1A1 (0.50) | LMNAKMT2A | |
| SCHEMBL3835497 | 0.71 | PRSS1 (0.31) | PRSS1PRSS2C1SPRSS3RECQL | |
| SCHEMBL441463 | 0.71 | MAPK1 (0.33) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |