Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972962 | 0.99 | LTA4H (0.46) | LTA4HGRIN2BALDH1A1BLMKDM1A | |
| Hydrochloric Acid SCHEMBL7983445 | 0.80 | CHRM3 (0.37) | CHRM4 | |
| SCHEMBL7982426 | 0.77 | LTA4H (0.47) | LTA4HGRIN2BALDH1A1BLMKDM1A | |
| Hydrochloric Acid SCHEMBL7971795 | 0.77 | LTA4H (0.47) | LTA4HGRIN2BALDH1A1BLMKDM1A | |
| SCHEMBL7989635 | 0.75 | LTA4H (0.45) | LTA4HGRIN2BCHRM4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7973177 | 0.74 | LTA4H (0.44) | LTA4HGRIN2BCHRM4CHRNB2CHRNA4 | |
| SCHEMBL7972411 | 0.74 | LTA4H (0.44) | LTA4HGRIN2BCHRM4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7985967 | 0.74 | LTA4H (0.44) | LTA4HGRIN2BCHRM4CHRNB2CHRNA4 | |
| SCHEMBL7986125 | 0.74 | LTA4H (0.44) | LTA4HGRIN2BALDH1A1BLMKDM1A | |
| SCHEMBL7971710 | 0.74 | LTA4H (0.44) | LTA4HGRIN2BALDH1A1BLMKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |